Understanding ENERGY METABOLISM IN HEALTH AND DISEASE

In the News…
UCSD Today – December 11th, 2025
Three UC San Diego Professors Inducted Into the National Academy of Inventors for 2025
Three professors at the University of California San Diego have been elected to the 2025 Class of Fellows of the National Academy of Inventors (NAI). Ping Liu, a professor of chemical and nano engineering at the UC San Diego Jacobs School of Engineering; Bernhard Palsson, a professor of bioengineering at the UC San Diego Jacobs School of Engineering; and Alan R. Saltiel, a professor of medicine and pharmacology at UC San Diego School of Medicine, are among 185 new Fellows announced by the NAI today.

In the News…
UCSD Today – December 10th, 2025
How the Immune System Stalls Weight Loss
Researchers at the University of California San Diego School of Medicine have uncovered a surprising new function for immune cells: preventing excess weight loss. In a recent study, the team demonstrates that when the body is exposed to physiological stressors, such as low temperature, neutrophils — a type of white blood cell — infiltrate fat tissue and release signals that slow fat breakdown.

In the News…
NIH – February 13, 2024
Obesity disrupts mitochondria, reduces fat-burning
Scientists identified a protein that triggers changes in mitochondria that lead to reduced fat-burning to promote weight gain in mice fed a high-fat diet.
The findings may point to potential new avenues for treating or preventing obesity in people.

In the News…
UCSD Today – January 29, 2024
How Obesity Dismantles Our Mitochondria
UC San Diego study reveals key mechanism behind obesity-related metabolic dysfunction

In the News…
Science Daily – February 6, 2020
Two enzymes control liver damage in NASH
After identifying a molecular pathway that allows nonalcoholic steatohepatitis (NASH) to progress into liver cell death, researchers were able to use these pathways to halt further liver damage.

In the News…
Eureka Alert – July 5th, 2018
Repurposed asthma drug shows blood sugar improvement among some diabetics
After 12 weeks of taking an anti-asthma drug, a subset of patients with type 2 diabetes showed a clinically significant reduction in blood glucose during a randomized, double blind, placebo-controlled clinical trial, report University of California San Diego School of Medicine and University of Michigan researchers.

In the News
Science Daily – February 8th 2018
Enzyme plays a key role in calories burned both during obesity and dieting
Ever wonder why obese bodies burn less calories or why dieting often leads to a plateau in weight loss? In both cases the body is trying to defend its weight by regulating energy expenditure. In a new paper, researchers identify the enzyme TANK-binding kinase 1 (TBK1) as a key player in the control of energy expenditure during both obesity and fasting.
More In the News…
- Fierce Biotech – February 8th 2018 – Fighting obesity by controlling inflammation
- The San Diego Union Tribune – September 22nd 2016 – How to battle cancer linked to obesity
- Science – October 10, 2014 – New class of fatty molecules battles diabetes in mice
- USA Today – July 1, 2013 – Study: Canker sore drug made mice skinny